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Inflammatory reaction to urate crystals in joints, bones and subcutaneous structures. Initially, a hyperacute arthritis that may progress to a chronic arthritis. Dietary excess (e.g., anchovies, sardine, shrimps, lobsters,mussels, sweetbreads, kidney, liver, and meat extracts), Hyperuricemia, Lead poisoning (moonshine), Kidney disease and some medications such as Aminophylline, Caffeine, Cytotoxic drugs, Diazepam, Diuretics and Ethanol ingestion are main risk factors of this condition.

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